15 min readUpdated Jan 2026

AI in Laboratory Informatics: Cutting Through the Hype

Some AI in labs is real and valuable. A lot is marketing language. Let's sort through what's actually happening.

Where AI Actually Delivers Value Today

Order Entry Automation (OCR)Working

91-98% accuracy on handwritten requisitions. 43.9% reduction in data entry time. Mature and valuable.

Missing Information DetectionWorking

ML models identify orders likely to cause denials. Catches issues before processing starts.

Billing ValidationWorking

Pattern matching against payer rules. Labs using intelligent validation see denial rates drop below industry average.

Specimen Quality AssessmentEmerging

Computer vision detecting hemolysis, lipemia, icterus. Technology improving rapidly.

Where AI Falls Short (For Now)

Clinical Decision Support

Regulatory barriers, liability concerns, data requirements, context complexity. AI can flag unusual results, but humans make decisions.

Predictive Maintenance

Requires years of clean operational data most labs don't have. Rules-based monitoring works today; truly predictive AI is still emerging.

Autonomous Operations

The 'lights-out lab' doesn't exist. Labs deal with endless exceptions requiring human judgment.

Red Flags When Evaluating "AI-Powered" Products

Vague claims without explanation of what the AI actually does
No specifics on training data
No accuracy metrics with confidence intervals
'It learns from your data' without detail
No explanation of failure modes

Questions to Ask Vendors

  1. 1What specific problem does the AI solve?
  2. 2What data was the model trained on?
  3. 3What's the accuracy in production (not idealized conditions)?
  4. 4How does it handle edge cases?
  5. 5What human oversight is required?
  6. 6How is the model updated and improved?

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